Hemodialyzer mass transfer-area coefficients for urea increase at high dialysate flow rates
نویسندگان
چکیده
منابع مشابه
Effect of Low Dialysate Flow Rate on Hemodialyzer Mass Transfer Area Coefficients for Urea and Creatinine.
Recent work has shown that the dialyzer mass transfer area coefficient (Ko A) for urea increases when the dialysate flow rate is increased from 500 to 800 mL/min. In this study we determined urea and creatinine clearances for two commercial dialyzers containing polysulfone hollow fibers in vitro at 37°C, a nominal blood flow rate of 300 mL/ min, and dialysate flow rates (Qd ) ranging from 100 t...
متن کاملIncreasing dialysate flow and dialyzer mass transfer area coefficient to increase the clearance of protein-bound solutes.
Clinical hemodialysis systems achieve high single pass extraction of small solutes that are not bound to plasma proteins. But they clear protein-bound solutes much less effectively. This study examines the extent to which clearance of a protein-bound test solute is improved by increasing the dialyzer mass transfer area coefficient (KoA) and the dialysate flow rate (Qd). A reservoir containing t...
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Usually, in concentration polarization models, the mass transfer coefficient is an unknown parameter. Also, its variation with changing experimental circumstances is in question. In the literature, many relationships can be found to describe the mass transfer coefficient under various conditions, as well as various corrections for deviating behaviour during ultrafiltration. To obtain reliable m...
متن کاملEffect of increasing dialysate flow rate on diffusive mass transfer of urea, phosphate and β2-microglobulin during clinical haemodialysis
BACKGROUND Diffusive clearance depends on blood and dialysate flow rates and the overall mass transfer area coefficient (K(o)A) of the dialyzer. Although K(o)A should be constant for a given dialyzer, urea K(o)A has been reported to vary with dialysate flow rate possibly because of improvements in flow distribution. This study examined the dependence of K(o)A for urea, phosphate and β(2)-microg...
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Turbulence structure on the gas side of a wavy stratified flow was experimentally investigated in a near horizontal 18.7 cm (H) 10 cm (W) 5.5m (L) rectangular duct.By applying the Variable Interval Time Averaging (VITA) technique to the hot wire anemometer measurements frequency of occurrence of turbulent events were detected near the air-water interface. Experimental results showed that fr...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1997
ISSN: 0085-2538
DOI: 10.1038/ki.1997.274